Background: Arginase I, encoded by the ARG1 gene, is an enzyme that catalyzes the conversion of arginine to ornithine in the urea cycle; mutations in this gene has recently been reported to be associated with dilated cardiomyopathy (DCM) in Pakistan. The present study aimed to investigate the relationship between ARG1 gene mutations and DCM in the Han Chinese population.

中文翻译：

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ARG1基因的常见变异有助于汉族人群发生扩张型心肌病的风险。

背景：由ARG1基因编码的精氨酸酶I是一种在尿素循环中催化精氨酸向鸟氨酸转化的酶。最近有报道称该基因的突变与巴基斯坦扩张型心肌病（DCM）有关。本研究旨在调查汉族人群中ARG1基因突变与DCM之间的关系。