Introduction. People with Parkinson’s disease (PD) have lower life satisfaction (LS) than healthy peers. No study has yet identified predictors of LS in people with PD. Such information would be valuable for health care and future interventions that aim to maintain or increase LS. Aim. To examine how LS evolved in people with PD over a 3-year period, as well as to identify predictive factors of LS. Methods. We used data from baseline assessments and a 3-year follow-up of 163 people with PD (baseline, mean age 68 years; median PD duration 8 years, 35% women). LS was assessed with item 1 of the Life Satisfaction Questionnaire (LiSat-11). Dichotomized LS data from the 3-year follow-up were used as the dependent variable in multivariable logistic regression analyses. In the first step, independent variables included baseline information on sex, education, general self-efficacy, motor symptoms, perceived walking difficulties, fall-related activity avoidance, and difficulties with/need help in activities of daily living. At the second step, depressive symptoms were added as an independent variable. Results. The proportion of those who reported being satisfied with their lives reduced from 63.2% at baseline to 49.7% 3 years later (). When depressive symptoms were not included in the analysis, general self-efficacy (odds ratio, OR = 1.081; 95% CI = 1.019–1.147) and perceived walking difficulties (OR = 0.962; 95% CI = 0.929–0.997) were significant () predictors of LS 3 years later. With depressive symptoms included, the influence of walking difficulties diminished, and depressive symptoms (OR = 0.730; 95% CI = 0.607–0.877) and general self-efficacy (OR = 1.074; 95% CI = 1.010–1.142) were the only significant predictors of LS 3 years later. Conclusions. LS is reduced over a 3-year period. The study suggests that perceived walking difficulties, general self-efficacy, and depressive symptoms are important predictors of LS in people with PD.

中文翻译：

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预测帕金森病患者的生活满意度。

简介。帕金森病 (PD) 患者的生活满意度 (LS) 低于健康同龄人。尚无研究确定 PD 患者 LS 的预测因子。这些信息对于旨在维持或增加 LS 的医疗保健和未来干预措施非常有价值。瞄准。研究 LS 在 3 年内如何在 PD 患者中演变，并确定 LS 的预测因素。方法. 我们使用了来自基线评估的数据和对 163 名 PD 患者的 3 年随访数据（基线，平均年龄 68 岁；中位 PD 持续时间 8 年，35% 为女性）。LS 使用生活满意度问卷 (LiSat-11) 的第 1 项进行评估。来自 3 年随访的二分法 LS 数据被用作多变量逻辑回归分析中的因变量。在第一步中，自变量包括关于性别、教育、一般自我效能感、运动症状、感知步行困难、与跌倒相关的活动回避以及日常生活活动中的困难/需要帮助的基线信息。第二步，将抑郁症状作为自变量添加。结果. 对生活感到满意的人比例从基线时的 63.2% 下降到 3 年后的 49.7%（）。当分析中不包括抑郁症状时，一般自我效能感（优势比，OR = 1.081；95% CI = 1.019-1.147）和感知步行困难（OR = 0.962；95% CI = 0.929-0.997）是显着的（) 3 年后 LS 的预测因子。包括抑郁症状，行走困难的影响减弱，抑郁症状（OR = 0.730；95% CI = 0.607-0.877）和一般自我效能感（OR = 1.074；95% CI = 1.010-1.142）是唯一显着的3 年后 LS 的预测因子。结论。LS 在 3 年内减少。该研究表明，感知步行困难、一般自我效能感和抑郁症状是 PD 患者 LS 的重要预测因素。