Abstract Fe3O4@SiO2-L-proline nanoparticles have been used as an effective catalyst for the preparation of pyrimidines by three-component reactions of 1,3-dimethylbarbituric acid, aromatic aldehydes and 4-methyl aniline or 4-methoxy aniline under reflux condition in ethanol. Fe3O4@SiO2-L-proline nanoparticles have been characterized by scanning electronic microscopy (SEM), powder X-ray diffraction (XRD), vibrating sample magnetometer (VSM), thermal gravimetric analysis (TGA), energy dispersive X-ray (EDS), dynamic light scattering (DLS) and FT-IR spectroscopy. This method provides several advantages including, the reusability of the catalyst, low catalyst loading, atom economy, short reaction times and high yields of products.

中文翻译：

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Fe3O4@SiO2-L-脯氨酸纳米颗粒合成嘧啶

摘要 Fe3O4@SiO2-L-脯氨酸纳米颗粒已被用作一种有效的催化剂，通过1,3-二甲基巴比妥酸、芳香醛和4-甲基苯胺或4-甲氧基苯胺在回流条件下的三组分反应制备嘧啶。乙醇。Fe3O4@SiO2-L-脯氨酸纳米粒子已通过扫描电子显微镜（SEM）、粉末X射线衍射（XRD）、振动样品磁强计（VSM）、热重分析（TGA）、能量色散X射线（EDS）表征、动态光散射 (DLS) 和 FT-IR 光谱。该方法提供了几个优点，包括催化剂的可重复使用性、催化剂负载量低、原子经济性、反应时间短和产品收率高。