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Comparative Study in Different Filters for Efficient Sterile Filtration
Bulletin of the Korean Chemical Society ( IF 2.3 ) Pub Date : 2020-07-29 , DOI: 10.1002/bkcs.12073
Hyun Ho An 1 , Byung Seok Moon 2 , Hyun Sik Park 1 , Hong Jin Lee 1 , Sang Ju Lee 3 , Seung Jun Oh 3 , Bom Sahn Kim 2 , Byung Chul Lee 1, 4 , Won Woo Lee 1 , Sang Eun Kim 1, 4, 5
Affiliation  

Simple membrane filtration is suitable as a terminal sterilization method for radiopharmaceuticals due to their short half‐life and radiation exposure of process operator. However, it often adheres to the filter membrane and causes a considerable loss of radioactivity. We herein describe the investigation of sterile filtration performance varying individual sterile filters in order to identify the optimal sterile filter on demand for lipophilic radiopharmaceuticals.

中文翻译:

不同过滤器进行高效无菌过滤的比较研究

简单的膜过滤由于其半衰期短和过程操作员的辐射暴露而适合作为放射性药物的最终灭菌方法。但是,它经常粘附在滤膜上,并导致放射性的显着损失。我们在本文中描述了对无菌过滤性能的研究,其改变了各个无菌过滤器,以便根据亲脂性放射性药物的需求确定最佳的无菌过滤器。
更新日期:2020-07-29
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