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Indian T. mentagrophytes squalene epoxidase erg1 double mutants show high proportion of combined fluconazole and terbinafine resistance
Mycoses ( IF 4.1 ) Pub Date : 2020-09-23 , DOI: 10.1111/myc.13150
Anke Burmester 1 , Uta-Christina Hipler 1 , Silke Uhrlaß 2 , Pietro Nenoff 2 , Archana Singal 3 , Shyam B Verma 4 , Peter Elsner 1 , Cornelia Wiegand 1
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The Indian ITS genotype VIII Trichophyton mentagrophytes population shows a high amount of different erg1 (ergosterol) mutants encoding for squalene epoxidase, which catalyses the first step of ergosterol biosynthesis.

中文翻译:

印度须癣角鲨烯环氧化酶erg1双突变体表现出高比例的氟康唑和特比萘芬联合耐药性

印度 ITS 基因型 VIII 毛癣菌种群显示出大量编码角鲨烯环氧化酶的不同 erg1(麦角甾醇)突变体,该酶催化麦角甾醇生物合成的第一步。
更新日期:2020-09-23
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