Four new nickel (II) complexes with bis(benzimidazole)thio- and selenoether-based ligands have been synthesized and characterized in the solid state by elemental analysis, IR, magnetic susceptibility and X-ray crystallography, and in solution by FAB⁺ mass spectrometry, UV–vis spectroscopy and cyclic voltammetry. Single-crystal X-ray diffraction analysis of the compounds revealed octahedral geometries for all nickel centers. Three of the four complexes are dimers with chloride bridges between the two Ni(II) ions. However, in solution all complexes have a monomeric formulation, based on mass spectrometry and osmometry measurements. The complexes were also screened for their cytotoxic activity on human cell lines (HeLa, SK-LU-1 and HEK-293), and compared with a related Cu(II) complex.

合成了四种具有双（苯并咪唑）硫基和硒醚基配体的新型镍（II）配合物，并通过元素分析，红外，磁化率和X射线晶体学表征了其固态，并通过FAB ⁺质谱在溶液中对其进行了表征，紫外可见光谱和循环伏安法。化合物的单晶X射线衍射分析显示了所有镍中心的八面体几何形状。四个络合物中的三个是在两个Ni（II）离子之间具有氯桥的二聚体。但是，在溶液中，基于质谱和渗透压测量，所有配合物均具有单体配方。还筛选了复合物对人细胞系（HeLa，SK-LU-1和HEK-293）的细胞毒活性，并与相关的Cu（II）复合物进行了比较。