Background/Objective: Impaired Inhibitory Control (IC) is a core feature of psychotic disorders and is related with impaired social functioning in people experiencing psychosis. Despite research showing the benefits of mindfulness over IC in the general population, no study has assessed its effects on IC in psychoses. The aim of our study was to assess the effectiveness of a mindfulness-based intervention combined with integrated rehabilitation treatment in a sample of people diagnosed of psychotic disorders. Method: Fifty-six patients diagnosed with psychotic disorder were recruited and randomly allocated either to integrated rehabilitation treatment or integrated rehabilitation treatment enhanced with 26 mindfulness group sessions. Measures comprised PANSS interview, MAAS scale, and Stroop Color Word Test (SCWT). The primary outcome variable was the performance in the non-congruent trials of the SCWT. Results: There were no differences between groups at baseline. At post-treatment patients allocated to mindfulness group increased their scores in non-congruent trials of SCWT and in MAAS. At post-treatment mindfulness group scored higher than integrated rehabilitation treatment in MAAS. Conclusions: Data suggest that mindfulness added to integrated rehabilitation treatment may improve IC in psychosis. Results are convergent with prior works about the effect of mindfulness over cognitive performance in general population.

背景/目的：抑制性控制障碍（IC）是精神病的核心特征，与患有精神病的人的社会功能受损有关。尽管有研究表明，在普通人群中，正念比IC具有益处，但尚无研究评估其对精神病患者IC的影响。我们研究的目的是评估被诊断为精神病患者的基于正念干预与综合康复治疗相结合的有效性。方法：招募了56名诊断为精神病的患者，并随机分配至综合康复治疗或通过26个正念小组会议加强的综合康复治疗。措施包括PANSS面试，MAAS量表和Stroop颜色文字测试（SCWT）。主要结果变量是SCWT在非一致试验中的表现。结果：基线时各组之间无差异。在治疗后，分配给正念组的患者在SCWT和MAAS的非一致性试验中得分更高。在治疗后，正念组的得分高于MAAS中的综合康复治疗。结论：数据表明，在综合康复治疗中增加正念可能会改善精神病的IC。结果与关于正念对一般人群认知表现的影响的先前研究相吻合。