Gugguluthiktham Kashayam (GTK) is the decoction form of Panchatikta Guggulu Ghrita, a classical Ayurvedic formulation used for treating various diseases like skin disorders, ulcers, sinus, asthma, cardiac diseases, arthritis, and cancer. Tandem mass spectroscopic analysis of GTK was carried out by different ionization techniques such as electro spray ionization (ESI) and atmospheric pressure chemical ionization (APCI) in both positive and negative modes using Quadrupole Time-of-Flight (Q-TOF) mass spectroscopy. Data processing of molecular ions obtained by ESI and APCI mass fragmentation led to the identification of several phytoconstituents belonging to various classes of compounds such as phenolics, flavonoids, and coumarins. The study concluded that GTK contains variety of phytochemicals with numerous biological properties that might be responsible for its various therapeutic effects.

中文翻译：

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通过串联质谱分析和多种电离技术对多草药配方进行化学分析

Gugguluthiktham Kashayam（GTK）是Panchatikta Guggulu Ghrita的汤剂，这是一种经典的印度草药制剂，用于治疗各种疾病，如皮肤疾病，溃疡，鼻窦，哮喘，心脏病，关节炎和癌症。GTK的串联质谱分析是使用四极杆飞行时间（Q-TOF）质谱通过正离子和负离子两种不同的电离技术（例如电喷雾电离（ESI）和大气压化学电离（APCI））进行的。通过ESI和APCI质量裂解获得的分子离子的数据处理导致鉴定了属于各种化合物（例如酚类，类黄酮和香豆素）的几种植物成分。