ABSTRACT Backround and aim: To evaluate the sensitisation to molecular components in atopic dermatitis patients with the use of Multiplex ISAC testing. Method: The complete dermatological and allergological examination including the examination of the sensitisation to molecular components with Multiplex ISAC testing was performed. Results and conclusion: Eighty one patients were examined – 40 men, 41 women, average age 41.7 years. The positivity was recorded most frequently to molecular components of timothy, birch, house dust mite, animals dander, bermuda grass, peach, apple, hazel pollen, kiwi, peanut and hazelnut, Alternaria and Aspergillus. Molecular components such as Equ c 1 (Horse), Alt a 6 (Alternaria), Fel d 1, Fel d 4 (Cat) and Can f 1, Can f 5 (Dog) are recorded with the significant higher occurrence simultaneously in patients suffering from severe form of AD, asthma bronchiale and allergic rhinitis; these molecular components play the most important role in the atopic march.

中文翻译：

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特应性皮炎患者对分子成分的敏感性，与支气管哮喘和过敏性鼻炎的关系

摘要 背景和目的：使用多重 ISAC 测试评估特应性皮炎患者对分子成分的敏感性。方法：进行了完整的皮肤病学和过敏学检查，包括使用多重 ISAC 测试检查对分子成分的敏感性。结果和结论： 81 名患者接受了检查——40 名男性，41 名女性，平均年龄 41.7 岁。最常记录阳性的分子成分有蒂莫西、桦木、屋尘螨、动物皮屑、百慕大草、桃、苹果、榛子花粉、猕猴桃、花生和榛子、链格孢属和曲霉属。分子成分，例如 Equ c 1 (Horse)、Alt a 6 (Alternaria)、Fel d 1、Fel d 4 (Cat) 和 Can f 1，Can f 5 (Dog) 在患有严重 AD、支气管哮喘和过敏性鼻炎的患者中同时出现显着更高的发生率；这些分子成分在特应性进军中发挥着最重要的作用。