Malassezia spp. are lipid-dependent yeasts, inhabiting the skin and mucosa of humans and animals. They are involved in a variety of skin disorders in humans and animals and may cause bloodstream infections in severely immunocompromised patients. Despite a tremendous increase in scientific knowledge of these yeasts during the last two decades, the epidemiology of Malassezia spp. related to fungemia remains largely underestimated most likely due to the difficulty in the isolation of these yeasts species due to their lipid-dependence. This review summarizes and discusses the most recent literature on Malassezia spp. infection and fungemia, its occurrence, pathogenicity mechanisms, diagnostic methods, in vitro susceptibility testing and therapeutic approaches.

马拉色菌属spp。是脂类依赖性酵母，栖息于人类和动物的皮肤和粘膜。它们涉及人类和动物的多种皮肤疾病，并可能在严重免疫受损的患者中引起血流感染。尽管在过去的二十年中，这些酵母的科学知识有了巨大的增长，但流行病学马拉色菌属spp。与真菌血症有关的酵母菌仍然很大程度上被低估了，这很可能是由于这些酵母菌由于其脂质依赖性而难以分离。这篇综述总结并讨论了有关马拉色菌属spp。感染和真菌病，其发生，致病机理，诊断方法，体外 药敏试验和治疗方法。