Visible‐Light‐Driven Remote C−H Chlorination of Aliphatic Sulfonamides with Sodium Hypochlorite,Asian Journal of Organic Chemistry

当前位置： X-MOL 学术 › Asian J. Org. Chem. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Visible‐Light‐Driven Remote C−H Chlorination of Aliphatic Sulfonamides with Sodium Hypochlorite
Asian Journal of Organic Chemistry ( IF 2.8 ) Pub Date : 2020-07-28 , DOI: 10.1002/ajoc.202000354
Yanshuo Zhu ₁ , Juan‐Juan Wang ₁ , Danhua Wu ₁ , Wei Yu ₁

Affiliation

The C(sp³)−H chlorination of aliphatic sulfonamides was realized by visible‐light photoredox catalysis with Ru(bpy)₃Cl₂ as photocatalsyt and NaOCl⋅5H₂O crystals as the chlorinating agent. The reaction proceeds in a tandem pattern of N−H chlorination and Hofmann‐Löffler‐Freytag chlorination. A variety of differently substituted sulfonamides were chlorinated in this way in high yield. A radical‐chain mechanism is proposed for the reaction on the basis of experimental evidence.

中文翻译：

次氯酸钠对脂肪族磺酰胺的可见光远程CH氯化反应

的C（SP ³）-H脂族磺酰胺的氯化物通过可见光photoredox催化用的Ru（联吡啶）实现₃氯₂作为photocatalsyt和NaOCl⋅5H ₂ ö晶体作为氯化剂。反应以N-H氯化和Hofmann-Löffler-Freytag氯化的串联方式进行。以这种方式高产率地氯化了各种不同取代的磺酰胺。在实验证据的基础上，提出了自由基链反应机制。

更新日期：2020-07-28

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11