Microbial bioremediation of multimetal contaminated wastewater can mitigate its environmental toxicity and human health risk. A multimetal tolerating fungus Aspergillus flvaus CR500, able to tolerate As (2000 mg/L), Ni (1600 mg/L), Mn (1600 mg/L), Pb (1200 mg/L), Cr (800 mg/L), Cu (200 mg/L) and Cd (100 mg/L), evident by the tolerance index of 0.22, 0.16, 0.19, 0.09, 0.15, 0.12 and 0.29 respectively A. flavus CR500 adopted multifarious biochemical (enzymatic and non-enzymatic) and morphological strategies (observed by scanning electron microscopic analysis) to deals with As, Pb and Ni toxicity. During the batch study, isolate CR500 could able to remove 99.0, 97.7 and 73.1% of As, Pb and Ni respectively from individual metal contaminated potato dextrose broth (PDB) medium via bioaccumulation and surface adsorption mechanism. A. flavus CR500 also exhibited excellent multimetal (As, Ni, Pb and Cr) removal potential from simulated wastewater (SWW) and Tannery wastewater (TWW) with a high amount of biomass production rate. The removal from 5 mg/L of each metal amended SWW was 97.5, 93.3, 82.2 and 46.6% for As, Pb, Cr and Ni respectively. The toxicity of fungal treated metal solution was reduced, observed from good germination rate and growth of Vigna radiata seeds. Thus A. flavus CR500 has single as well as multimetal removal ability and can be used for ecofriendly treatment of multimetal contaminated wastewater.

微生物对多金属污染废水的生物修复可以减轻其环境毒性和人类健康风险。一种多金属耐受性黄曲霉菌CR500，能够耐受As（2000 mg / L），Ni（1600 mg / L），Mn（1600 mg / L），Pb（1200 mg / L），Cr（800 mg / L） ，Cu（200 mg / L）和Cd（100 mg / L），分别以0.22、0.16、0.19、0.09、0.15、0.12和0.29的耐受指数显示CR500采用多种生化（酶促和非酶促）和形态学策略（通过扫描电子显微镜分析观察）来应对As，Pb和Ni的毒性。在批量研究过程中，分离物CR500可以通过生物累积和表面吸附机制从单个金属污染的马铃薯葡萄糖肉汤（PDB）培养基中分别去除99.0％，97.7％和73.1％的As，Pb和Ni。黄曲霉CR500还显示出从模拟废水（SWW）和皮革厂废水（TWW）中去除多金属（As，Ni，Pb和Cr）的出色潜力，并具有很高的生物质生产率。从5 mg / L的各种金属中，SWW，As，Pb，Cr和Ni的去除率分别为97.5、93.3、82.2和46.6％。真菌处理的金属溶液的毒性降低，从良好的发芽率和生长观察绿豆种子。因此黄曲霉CR500具有单以及多金属的去除能力，并且可以被用于多金属污染的废水的生态友好的处理。