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Numerical simulation of the aqueous humor flow in the eye drainage system; a healthy and pathological condition comparison.
Medical Engineering & Physics ( IF 2.2 ) Pub Date : 2020-07-28 , DOI: 10.1016/j.medengphy.2020.07.010
G J Martínez Sánchez 1 , C Escobar Del Pozo 2 , J A Rocha Medina 3 , J Naude 1 , A Brambila Solorzano 1
Affiliation  

The present work describes the motion of aqueous humor through the anterior chamber and the trabecular drainage system, considering several distributions of the collector channels. The 3D computational model, implemented into the open-source software, was reconstructed from an optical coherence tomography. The model has been employed to simulate the aqueous humor dynamics considering buoyancy effects. The presence of the anterior chamber, the trabecular meshwork, and the Schlemm’s canal were taken into consideration with 14 different distributions of collector channels. The influence of collector channels position on the intraocular pressure and shear stress has been analyzed, for a healthy and a glaucomatous condition. Aqueous humor velocity, pressure, temperature, wall shear stress, skin friction coefficient and Nusselt number, are presented for the different cases. The results indicate that the position of the collector channels has a strong influence on the wall shear stress on the Schlemm’s canal and collector channels.



中文翻译:

眼引流系统中房水流动的数值模拟;健康和病理状态的比较。

目前的工作描述了房水通过前房和小梁引流系统的运动,考虑了收集器通道的几种分布。实施到开源软件中的 3D 计算模型是从光学相干断层扫描中重建的。该模型已被用于模拟考虑浮力效应的房水动力学。前房、小梁网和施累姆氏管的存在被考虑到收集器通道的 14 种不同分布。分析了收集器通道位置对眼内压和剪切应力的影响,对于健康和青光眼状态。房水速度、压力、温度、壁剪切应力、皮肤摩擦系数和努塞尔数,针对不同的情况进行介绍。结果表明,收集器通道的位置对施累姆氏管和收集器通道的壁面剪应力有很大影响。

更新日期:2020-08-01
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