Purpose

Aphasia is one of the most common complications after stroke and occurs in 21–38% of the patients during acute period. The present study aimed to investigate the response to speech and language therapy according to artery involvement and lesion location in patients with post-stroke aphasia.

Method

The medical records of 107 patients with post-stroke aphasia (mean age, 58.8 ± 14.8 years) who were admitted to a single rehabilitation center for usual care after stroke were reviewed. Location of the ischemic lesion and involved artery was determined assessing the brain MRI of the patients. All the patients received 24 sessions speech and language therapy (3 days a week) as a part of 8-week rehabilitation program. Evaluation of the aphasia was performed with Gülhane Aphasia Test-2 (GAT-2) at baseline and at the end of the rehabilitation program.

Results

Baseline GAT-2 scores was significantly worse in patients with middle cerebral artery (MCA) involvement compared to patients with other artery involvements (p = 0.007). While the GAT-2 scores of patients with MCA involvement were improved significantly after speech and language therapy (p < 0.001), the changes in those with anterior cerebral artery (ACA) and posterior cerebral artery (PCA) involvements were not significant (p > 0.05).

Conclusions

The present findings suggested that speech functions might be more affected in ischemic lesion of MCA and response to SLT might be better in patients with MCA involvement.

中文翻译：

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根据卒中后失语症的动脉介入程度和病变部位对言语和语言疗法的反应。

目的

失语症是中风后最常见的并发症之一，在急性期有21–38％的患者发生。本研究旨在根据卒中后失语症患者的动脉受累情况和病变位置调查对言语和语言疗法的反应。

方法

回顾了107例卒中后失语症（平均年龄58.8±14.8岁）的患者的病历，这些患者在卒中后被送往单个康复中心进行常规护理。确定缺血性病变和受累动脉的位置，以评估患者的脑部MRI。作为8周康复计划的一部分，所有患者均接受了24次语言和语言治疗（每周3天）。在基线和康复计划结束时，使用GülhaneAphasia Test-2（GAT-2）对失语症进行评估。

结果

与其他动脉受累患者相比，大脑中动脉受累患者的基线GAT-2评分显着更差（p = 0.007）。言语和语言治疗后，患有MCA的患者的GAT-2评分显着改善（p <0.001），而患有前脑动脉（ACA）和后脑动脉（PCA）的患者的变化不明显（p> 0.05）。

结论

本研究结果表明，MCA缺血性病变中，言语功能可能受到更大影响，MCA受累患者对SLT的反应可能更好。