New cryo-electron microscopy structures of the mitochondrial Ca²⁺ uniporter ion channel complex in various conformations reveal channel gating regulation by Ca²⁺-dependent unblock of the channel pore by MICU1.

中文翻译：

---

打开 MCU 的塞子，让钙流动。

不同构象的线粒体Ca ²⁺单向转运蛋白离子通道复合物的新冷冻电子显微镜结构揭示了MICU1对通道孔的Ca ²⁺依赖性解封的通道门控调节。