A biodegradable poly-lactic acid (PLA) microneedle array composed of needles with a maximum length of 3 mm and an aspect ratio of up to approximately 18 was fabricated by drawing lithography. In the proposed fabrication method, the melted polymer is stretched twice. The approximate length is set in the first stretch, and the tip is sharpened in the second stretch. In the first stretch, by changing the thickness of the PLA sheet, PLA pillars with various lengths are fabricated. By defining the initial length of the needle, it is possible to set a wide range of aspect ratios and lengths. In the second stretch, it is possible to control the final aspect ratio and length of the needle, as well as the shape of its tip by changing the temperature and stretch speed of the PLA pillars. Finally, it was confirmed that the needle can pierce the surface of artificial skin and porcine skin.

通过拉伸光刻技术，制作了由最大长度为3 mm，长宽比最大为约18的针组成的可生物降解的聚乳酸（PLA）微针阵列。在提出的制造方法中，将熔融的聚合物拉伸两次。在第一个拉伸段中设置近似长度，在第二个拉伸段中，尖端变尖。在第一次拉伸中，通过更改PLA板的厚度，可以制造出各种长度的PLA柱。通过定义针的初始长度，可以设置宽高比和长度的范围。在第二次拉伸中，可以通过更改PLA柱的温度和拉伸速度来控制针的最终长宽比和长度以及针尖的形状。最后，