This review will summarize the research information regarding the regenerative potential of dental stem cells for the treatment of neurodegenerative disorders. As compared to existing treatment modalities, the stem cell therapy seems promising, and accumulating evidences about the differentiation of stem cells into various lineages are proving it. The incidence of neurodegenerative diseases such as Alzheimer’s, Parkinson’s, stroke, and peripheral neuropathy is increasing due to the rise in life expectancies of people which have put a huge burden on economies. Finding a promising treatment could benefit not only the patients but also the communities. Dental stem cells hold a great potential to differentiate into neuronal cells. Many studies have reported the differentiation potential of the dental stem cells with the presence of neuronal lineage markers. In this review, we conferred how the use of dental stem cells can benefit the above-mentioned bedridden diseases.

中文翻译：

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牙科干细胞的神经再生潜力：简要回顾

本综述将总结有关牙科干细胞在治疗神经退行性疾病方面的再生潜力的研究信息。与现有的治疗方式相比，干细胞疗法似乎很有希望，并且越来越多的证据表明干细胞分化为各种谱系。由于人们预期寿命的增加，给经济带来了巨大负担，因此神经退行性疾病（例如阿尔茨海默氏症、帕金森氏症、中风和周围神经病变）的发病率正在增加。找到一种有前途的治疗方法不仅可以使患者受益，还可以使社区受益。牙齿干细胞具有分化成神经元细胞的巨大潜力。许多研究报告了存在神经元谱系标记物时牙齿干细胞的分化潜力。在这篇综述中，我们讨论了使用牙科干细胞如何有益于上述卧床不起的疾病。