Mitochondrial dysfunction underlies a vast array of chronic disorders across the life span. The asymptotic limit theorems of information and control theories, supplemented by symmetry-breaking phase transition arguments adapted from physical theory, give deep insight into canonical mechanisms of cognition and regulation associated with such dysfunction. The probability models studied here can provide a foundation for the development of statistical tools useful in clinical and public health address of those disorders.

中文翻译：

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断裂的对称性：线粒体功能障碍的信息和控制理论视角

线粒体功能障碍是整个生命周期中大量慢性疾病的基础。信息和控制理论的渐近极限定理，辅以从物理理论改编的对称破缺相变论证，深入了解与这种功能障碍相关的认知和调节的典型机制。这里研究的概率模型可以为开发可用于临床和公共卫生解决这些疾病的统计工具奠定基础。