A series of novel dimethyl 7-((2S,3S)-3-((1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)methoxy)-3,6-dihydro-2H-pyran-2-yl)-4-(4-fluorophenyl)-9-oxo-8-phenyl-6-thia-1,2,8-triazaspiro[4.4]non-2-en-3-ylphosphonate 11a-g have been synthesized by the reaction of chalcone derivatives of (E)-5-benzylidene-2-((2S,3S)-3-((1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)methoxy)-3,6-dihydro-2H-pyran-2-yl)-3-phenylthiazolidin-4-one 10a-g with Bestmen Ohira reagent. The chemical structures of newly synthesized compounds have been elucidated by IR, NMR, MS and elemental analysis. The compounds 11a-g have been evaluated for their nematicidal activity against Dietylenchus myceliophagus and Caenorhabditis elegans. Compound 11b, 11c, 11g and 11f show appreciable nematicidal activity.

中文翻译：

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新型膦酰基噻唑并吡唑的合成及生物评价

一系列新的二甲基7-（（（2S，3S）-3-（（1-（4-氯苯基）-1 H -1,2,3-三唑-4-基）甲氧基）-3,6-二氢- 2 H-吡喃-2-基）-4-（4-氟苯基）-9-氧代-8-苯基-6-硫杂1,2,8-三氮杂螺[4.4]非-2-烯-3-基膦酸酯11a -g是通过（E）-5-亚苄基-2-（（2S，3S）-3-（（1-（4-氯苯基）-1 H -1,2,3- （三唑-4-基）甲氧基）-3,6-二氢-2 H-吡喃-2-基）-3-苯基噻唑烷酮-4-酮10a-g与Bestmen Ohira试剂。通过IR，NMR，MS和元素分析已经阐明了新合成化合物的化学结构。化合物11a-g已被评估其对食线菌和秀丽隐杆线虫的杀线虫活性。化合物11b，11c，11g和11f显示出明显的杀线虫活性。