Herein is provided an alternate, simple, multigram scale, efficient route for Biginelli reaction for synthesis of dihydropyrimidinones using urea, ethylacetatoacetate, and benzaldehyde with pivalic acid.

中文翻译：

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新戊酸辅助Biginelli反应合成二氢嘧啶酮和二氢硫嘧啶酮

本文提供了一种用于尿素，乙酰乙酸乙酯和苯甲醛与新戊酸的Biginelli反应合成二氢嘧啶酮的替代，简单，克级有效的途径。