The objective of our study was to perform phytochemical analysis and evaluate for cytotoxic activity of hydro alcoholic fraction (H1) of Trianthema decandra L. (Aizoaceae) against breast, liver and cervical cancers. Hydro alcoholic fraction was separated from methanolic extract, which was prepared by maceration method from aerial parts of T. decandra The GC-MS analysis confirms the presence of seventeen bioactive compounds which belongs to carbohydrates, terpenoids, alkaloids, cardiac glycosides, fatty acids and their esters or alcohols, and their presence were supported with Fourier Transform Infrared Spectroscopy (FT-IR) and preliminary phytochemical analysis. Most of the compounds are biologically active and are known to exhibit antimicrobial and cancer preventive properties. Hydro alcoholic fraction was subjected to morphological evaluation and MTT cell viability assay. It has exhibited significant cytotoxic activity and their IC₅₀ values were determined as 165.22 + 1.53 mg/ml, 175.28 + 1.7 mg/ml and 201.93 + 1.33 mg/ml against MCF-7, HeLa and HepG2 cancer cells, respectively. This bioactive fraction has exhibited cytotoxicity relatively more against breast cancer than cervical and liver cancers.

中文翻译：

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三角叶桑an的酒精成分的植物化学研究和细胞毒活性

我们研究的目的是进行植物化学分析，并评估木an（Tianthema decandra L.（Aizoaceae））的酒精部分（H1 ）对乳腺癌，肝癌和宫颈癌的细胞毒性。从甲醇提取物中分离出醇馏分，甲醇提取物是通过浸软法从山T的地上部分制备的。GC-MS分析确认存在十七种生物活性化合物，这些化合物属于碳水化合物，萜类化合物，生物碱，强心苷，脂肪酸及其酯或醇，并且通过傅立叶变换红外光谱（FT-IR）和初步植物化学方法支持了它们的存在分析。大多数化合物具有生物活性，已知具有抗菌和预防癌症的性能。对醇级分进行形态评估和MTT细胞活力测定。它显示出显着的细胞毒性活性，其IC ₅₀值确定为165.22 + 1.53 mg / ml，175.28 + 1.7 mg / ml和201.93 +分别针对MCF-7，HeLa和HepG2癌细胞1.33 mg / ml。与宫颈癌和肝癌相比，这种生物活性成分对乳腺癌的细胞毒性相对更大。