Sucrose/H+ Symporters (SUTs) play an important role in plant growth and yield. They are involved in long distance transport of sucrose from source leaves to filling grains of cereals through a process called phloem loading. However, the molecular mechanism of sucrose transport through SUTs is not yet known. Understanding the key residues involved in sucrose transport can be helpful in developing high yielding varieties through genetic engineering, gene editing or allele mining. Here, the molecular model of OsSUT1 developed based on refined target-template alignment using Modeller software provides structural insights on the sucrose transport mechanism. We propose 13 putative sucrose binding residues and 11 putative H+ binding residues involved in sucrose/H+ co-transport in OsSUT1.

中文翻译：

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通过改良序列-基于模板比对的Oryza sativa L.Sucrose / H + Symporter1（OsSUT1）对蔗糖转运的结构见解

蔗糖/ H +转运蛋白（SUT）在植物生长和产量中起重要作用。它们参与了蔗糖从源叶到谷物充实谷物的长距离运输，这一过程称为韧皮部加载。然而，蔗糖通过SUT转运的分子机制尚不清楚。了解蔗糖运输中涉及的关键残基可能有助于通过基因工程，基因编辑或等位基因挖掘开发高产品种。在这里，使用Modeller软件基于精确的目标模板比对开发的OsSUT1分子模型提供了关于蔗糖转运机制的结构见解。我们提出了OsSUT1中参与蔗糖/ H +共转运的13个假定的蔗糖结合残基和11个假定的H +结合残基。