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Amplified AND logic platform for cell identification.
Chemical Communications ( IF 4.3 ) Pub Date : 2020-07-27 , DOI: 10.1039/d0cc04159a
Jiaoli Wang 1 , Jing Li , Shiyuan Liu , Xiangxian Meng , Xiaohai Yang , Jin Huang , Kemin Wang
Affiliation  

Herein, we developed an amplified AND logic platform (AALP) on a cell membrane, which integrated two DNA aptamers for cell recognition and localized catalytic hairpin assembly (LCHA) for signal amplification. The AALP could perform “AND” logic computing via a double-checked strategy of two biomarkers on similar cell surfaces and precisely label the target cells with an amplified fluorescence signal.

中文翻译:

用于细胞识别的扩增AND逻辑平台。

本文中,我们在细胞膜上开发了一个扩增的AND逻辑平台(AALP),该平台整合了两个用于细胞识别的DNA适体和用于信号放大的局部催化发夹组装(LCHA)。AALP可以通过在相似细胞表面上对两个生物标志物进行双重检查的策略来执行“ AND”逻辑计算并使用放大的荧光信号精确标记靶细胞。
更新日期:2020-09-24
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