Background: Patients with large, acute burn injuries are a major challenge for clinicians. The loss of skin barrier protection against micro-organisms combined with the induced immunosuppression after burn injury makes this population especially vulnerable to infection. For burn-injured patients who survive immediate management considerations and burn resuscitation after acute injury, sepsis remains the primary cause of death. The purpose of this article is to describe current strategies and innovations in burn sepsis prevention and management.

中文翻译：

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感染防治创新

背景：大面积急性烧伤患者是临床医生面临的主要挑战。对微生物的皮肤屏障保护的丧失与烧伤后诱导的免疫抑制相结合，使这一人群特别容易受到感染。对于在急性损伤后立即处理和烧伤复苏后幸存下来的烧伤患者，败血症仍然是主要的死亡原因。本文的目的是描述烧伤败血症预防和管理的当前策略和创新。