Safety and potential efficacy of cyclooxygenase-2 inhibitors in coronavirus disease 2019.,Clinical & Translational Immunology

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Safety and potential efficacy of cyclooxygenase-2 inhibitors in coronavirus disease 2019.
Clinical & Translational Immunology ( IF 5.8 ) Pub Date : 2020-07-26 , DOI: 10.1002/cti2.1159
Sean Wei Xiang Ong _{1,

2} , Wilnard Yeong Tze Tan _{1,

2} , Yi-Hao Chan ₃ , Siew-Wai Fong _{3,

4} , Laurent Renia ₃ , Lisa Fp Ng _{3,

5,

6} , Yee-Sin Leo _{1,

2,

7,

8} , David Chien Lye _{1,

2,

7,

8} , Barnaby Edward Young _{1,

2,

7}

Affiliation

While the safety of non‐steroidal anti‐inflammatory drugs in COVID‐19 has been questioned, they may be beneficial given the hyper‐inflammatory immune response associated with severe disease. We aimed to assess the safety and potential efficacy of cyclooxygenase‐2 (COX‐2) selective inhibitors in high‐risk patients.

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