Abstract Iron oxide nanoparticles (IONPs) with cubic shape was synthesized using a non-toxic solvent comprising of choline chloride (ChCl) and citric acid (CA). From the Tauc plot, the direct and indirect optical band gaps were found to be 2.53 eV and 1.7 eV respectively. Characteristic peaks in the Fourier transform infrared spectrum at 633 cm−1 and 587 cm−1 proved the presence of Fe-O bond linkage. XRD peaks evidenced the formation of a pure cubic magnetite (Fe3O4) without the presence of any other phases. From TEM analysis confirmed the nanoparticles to be in cubic shape with an average particle size 6.91 nm. Superparamagnetic behaviour was identified with saturation magnetization value of 0.97697 emu/g. From BET surface area analysis the pore diameter, pore volume and surface area were found to be 10.009 nm, 0.107 cm3/g and 27.313 m²/g respectively. EDAX analysis revealed the presence of only iron and oxygen, suggesting that the synthesized IONPs are highly pure. Rhodamine B was photo degraded upto 94 % under UV light irradiation. A dose dependent anticancer activity was envisioned from MTT assay. IC50 was found to be 14.14 µg/mL. The DES capped magnetite showed enhanced photo degradation of organic pollutant and showed excellent anticancer effect against CCL 241 human gastric cancer cells, hence it can be used in the treatment of industrial effluent and cancer.

中文翻译：

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使用深共晶溶剂轻松合成磁铁矿纳米立方体：对抗癌和光芬顿功效的洞察

摘要 使用由氯化胆碱 (ChCl) 和柠檬酸 (CA) 组成的无毒溶剂合成了立方体的氧化铁纳米粒子 (IONPs)。从 Tauc 图中，发现直接和间接光学带隙分别为 2.53 eV 和 1.7 eV。傅里叶变换红外光谱中 633 cm-1 和 587 cm-1 处的特征峰证明存在 Fe-O 键连接。XRD 峰证明形成了纯立方磁铁矿 (Fe3O4)，不存在任何其他相。TEM 分析证实纳米颗粒呈立方体形状，平均粒径为 6.91 nm。饱和磁化强度值为 0.97697 emu/g 时确定了超顺磁行为。从 BET 表面积分析发现孔径、孔体积和表面积为 10.009 nm、0.107 cm3/g 和 27。分别为 313 平方米/克。EDAX 分析显示仅存在铁和氧，表明合成的 IONP 是高纯度的。罗丹明 B 在紫外光照射下光降解达 94%。从 MTT 测定中设想了剂量依赖性抗癌活性。发现 IC50 为 14.14 µg/mL。DES封端的磁铁矿对有机污染物的光降解作用增强，对CCL 241人胃癌细胞显示出优异的抗癌作用，可用于工业废水和癌症的处理。