Abstract

l-ascorbic acid 2-phosphate magnesium (APMg) salt is a vitamin C derivative frequently used as a raw material in cell and tissue therapy. APMg is not only used as a replacement of the unstable ascorbate, but also shows additional cell-biological functionalities. However, its unknown structural characteristics hamper the mechanistic elucidation of its biological role. Therefore, different techniques were applied for APMg structure characterization. Firstly, the stoichiometric composition was characterized by its solvent, ligand and magnesium content. No crystals of APMg could be obtained; however, a single crystal of APNa, the sodium salt of l-ascorbic acid 2-phosphate, was successfully obtained and its crystal structure was elucidated. FT-IR was applied to further clarify the structure of solid APMg. Finally, the structure of APMg in aqueous solution was explored by potentiometric titration as well as FT-IR.

Graphic abstract

中文翻译：

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L-抗坏血酸2-磷酸镁的结构研究，它是细胞和组织治疗的原料。

摘要

升-抗坏血酸2-磷酸镁（APMg）盐是一种维生素C衍生物，经常被用作细胞和组织治疗的原料。APMg不仅可以替代不稳定的抗坏血酸，而且还具有其他细胞生物学功能。但是，其未知的结构特征妨碍了对其生物学作用的机理解释。因此，将不同的技术应用于APMg结构表征。首先，化学计量组成由其溶剂，配体和镁含量表征。无法获得APMg的晶体。然而，成功地获得了APNa的单晶，即1-抗坏血酸2-磷酸钠盐，并阐明了其晶体结构。FT-IR用于进一步澄清固体APMg的结构。最后，

图形摘要