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The Neurological Symptoms of Long COVID-19: A Comparison with other Neurological Conditions and Implications for Healthcare Services
medRxiv - Neurology Pub Date : 2020-09-18 , DOI: 10.1101/2020.07.21.20158816
Tamar Wildwing , Nicole Holt

Objective: In response to the rapid spread of COVID-19, this paper provides health professionals with better accessibility to available evidence, summarising findings from a systematic overview of systematic reviews of the neurological symptoms seen in patients with COVID-19. Implications of so-called Long Covid on neurological services and primary care and similarities with other neurological disorders are discussed. Methods: Firstly, a systematic overview of current reviews of neurological symptoms of COVID-19 was conducted. Secondly the implications of these findings are discussed in relation to the potential effect on neurological services and the similarities in the experience of patients with COVID-19 and those with other neurological disorders. Results: Twenty-nine systematic reviews were identified within seven databases, published between 11th April 2020 and 27th August 2020. The results indicated (so far), that COVID-19 exhibits two types of neurological symptoms; life threatening symptoms such as Guillain Barre Syndrome and encephalitis, and less devastating symptoms such as fatigue and myalgia. These so-called lesser symptoms appear to be emerging as longer-term for some sufferers and have been recently labelled Long Covid. When compared, these Long Covid symptoms are very similar to other neurological conditions such as Chronic Fatigue Syndrome (CFS) and Functional Neurological Disorder (FND). Conclusions: Implications for neurological healthcare services in the UK may include longer waiting times and a need for more resources (including more qualified health professionals). There is also a possible change-effect on perceptions of other neurological conditions such as CFS and FND, particularly for health professionals. Future research is recommended to explore changes in perceptions of neurological symptoms because of COVID-19, particularly for health professionals.

中文翻译:

长COVID-19的神经系统症状:与其他神经系统疾病的比较及其对医疗服务的启示

目的:针对COVID-19的迅速传播,本文为卫生专业人员提供了更好的可利用证据,并总结了对COVID-19患者所见神经系统症状的系统评价的系统综述。讨论了所谓的Long Covid对神经科服务和初级保健以及与其他神经系统疾病的相似性的影响。方法:首先,对当前对COVID-19的神经系统症状进行回顾的系统综述。其次,讨论了这些发现的含义,涉及对神经系统服务的潜在影响以及COVID-19患者和其他神经系统疾病患者经验的相似性。结果:在七个数据库中确定了29个系统评价,该结果发表于2020年4月11日至2020年8月27日之间。(到目前为止)结果表明,COVID-19表现出两种神经症状。危及生命的症状,如格林兰综合征和脑炎,以及破坏性较小的症状,如疲劳和肌痛。这些所谓的较小症状对于某些患者来说似乎是长期出现的,并且最近被标记为Long Covid。比较时,这些Long Covid症状与其他神经系统疾病(例如慢性疲劳综合症(CFS)和功能性神经系统疾病(FND))非常相似。结论:对英国神经系统医疗服务的影响可能包括更长的等待时间和对更多资源的需求(包括更多合格的医疗专业人员)。对于其他神经系统疾病(例如CFS和FND)的感知也可能产生变化,尤其是对于卫生专业人员。建议进行进一步的研究,以探讨COVID-19对神经系统症状的感知变化,特别是对于卫生专业人员。
更新日期:2020-09-20
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