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Viscum album L. homogenizer-assisted and ultrasound-assisted extracts as potential sources of bioactive compounds.
Journal of Food Biochemistry ( IF 3.5 ) Pub Date : 2020-07-25 , DOI: 10.1111/jfbc.13377 Azzurra Stefanucci 1 , Gokhan Zengin 2 , Eulogio J Llorent-Martinez 3 , Marilisa Pia Dimmito 1 , Alice Della Valle 1 , Stefano Pieretti 4 , Gunes Ak 2 , Kouadio Ibrahime Sinan 2 , Adriano Mollica 1
Journal of Food Biochemistry ( IF 3.5 ) Pub Date : 2020-07-25 , DOI: 10.1111/jfbc.13377 Azzurra Stefanucci 1 , Gokhan Zengin 2 , Eulogio J Llorent-Martinez 3 , Marilisa Pia Dimmito 1 , Alice Della Valle 1 , Stefano Pieretti 4 , Gunes Ak 2 , Kouadio Ibrahime Sinan 2 , Adriano Mollica 1
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Viscum album L. (Mistletoe) is one of the most famous plants in many countries utilized for several purposes. The current study aimed to describe chemical profiles and biological activities of homogenizer‐assisted extract (HAE) and ultrasound‐assisted extract (UAE)) of V. album parts (leaf, fruits, and seeds). Antioxidant (radical scavenging, reducing power, metal chelation, and phosphomolybdenum assays) and enzyme inhibitory properties (cholinesterases, amylase, glucosidase, and tyrosinase) were selected for biological evaluation. Chemical profiles were studied by HPLC‐MS/MS and 32 compounds were identified in the extracts; caffeoylquinic acids and its derivatives, dimethylated flavonoids were the most significant compounds. Generally, the leaf extracts exhibited the best antioxidant and enzyme inhibitory effects in our tests. Multivariate analysis was performed to obtain more information for these data, then strong correlations between total bioactive compounds and tested parameters were observed. The present findings encourage us to further investigate V. album as a potential candidate for pharmaceutical and nutraceutical applications.
中文翻译：
Viscum Album L.匀浆辅助和超声辅助提取物是生物活性化合物的潜在来源。
Viscum album L.（槲寄生）是许多国家/地区最有名的植物，有多种用途。目前的研究旨在说明化学性质和均质辅助提取物（HAE）和超声辅助萃取（UAE））的生物活性五张专辑零件（叶子，水果和种子）。选择抗氧化剂（自由基清除，还原能力，金属螯合和磷钼含量测定）和酶抑制特性（胆碱酯酶，淀粉酶，葡萄糖苷酶和酪氨酸酶）进行生物学评估。通过HPLC-MS / MS研究了化学特征，并在提取物中鉴定出32种化合物。咖啡酰奎尼酸及其衍生物，二甲基化类黄酮是最重要的化合物。通常，在我们的测试中，叶提取物表现出最好的抗氧化剂和酶抑制作用。进行多变量分析以获得这些数据的更多信息，然后观察到总生物活性化合物与测试参数之间的强相关性。目前的发现鼓励我们进一步调查V.专辑 作为制药和营养保健应用的潜在候选人。
更新日期：2020-09-14
中文翻译：
Viscum Album L.匀浆辅助和超声辅助提取物是生物活性化合物的潜在来源。
Viscum album L.（槲寄生）是许多国家/地区最有名的植物，有多种用途。目前的研究旨在说明化学性质和均质辅助提取物（HAE）和超声辅助萃取（UAE））的生物活性五张专辑零件（叶子，水果和种子）。选择抗氧化剂（自由基清除，还原能力，金属螯合和磷钼含量测定）和酶抑制特性（胆碱酯酶，淀粉酶，葡萄糖苷酶和酪氨酸酶）进行生物学评估。通过HPLC-MS / MS研究了化学特征，并在提取物中鉴定出32种化合物。咖啡酰奎尼酸及其衍生物，二甲基化类黄酮是最重要的化合物。通常，在我们的测试中，叶提取物表现出最好的抗氧化剂和酶抑制作用。进行多变量分析以获得这些数据的更多信息，然后观察到总生物活性化合物与测试参数之间的强相关性。目前的发现鼓励我们进一步调查V.专辑 作为制药和营养保健应用的潜在候选人。
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