This study investigated whether hydrogels comprising hydrophilic cationic polymers have similar bactericidal effects. Bacteria were seeded on hydrogels and agar and their viability was assessed with time. Cationic hydrogels displayed bactericidal effects upon long‐term bacterial contact. Furthermore, we assessed the areal density of cationic monomer unit of the cationic hydrogels, water content, and the initial elastic modulus. We examined correlations between each factor and bacterial death ratios; consequently, the bacterial death ratios were strongly correlated with the areal density of cationic hydrogel monomers. Elastic energy (W_el) generated at the cytomembrane ion‐binding region and the cationic hydrogel and the cytomembrane interfacial energy (W_f) were estimated; consequently, W_el exceeded W_f at higher contact areas. The cationic hydrogel may extract cytomembranes with a reasonable adsorption area. Therefore, cationic hydrogels may be used as probes for ultrasonic echo to sterilize medical equipment.

中文翻译：

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由亲水性聚合物制备的阳离子水凝胶的杀菌作用

这项研究调查了包含亲水性阳离子聚合物的水凝胶是否具有相似的杀菌作用。将细菌接种在水凝胶和琼脂上，并随时间评估其生存能力。阳离子水凝胶在长期细菌接触后显示出杀菌作用。此外，我们评估了阳离子水凝胶中阳离子单体单元的面密度，水含量和初始弹性模量。我们检查了每个因素与细菌死亡比率之间的相关性；因此，细菌的死亡率与阳离子水凝胶单体的面密度密切相关。在细胞膜离子结合区，阳离子水凝胶和细胞膜界面能（W _f）处产生的弹性能（W _el））被估计；因此，w ^ _EL超过W¯¯ _˚F在较高的接触面积。阳离子水凝胶可以提取具有合理吸附面积的细胞膜。因此，阳离子水凝胶可用作超声回波的探针以对医疗设备进行灭菌。