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The Role of MicroRNAs in Regulating Cytokines and Growth Factors in Coronary Artery Disease: The Ins and Outs.
Journal of Immunology Research ( IF 3.5 ) Pub Date : 2020-07-25 , DOI: 10.1155/2020/5193036
Armita Mahdavi Gorabi 1 , Nasim Kiaie 1 , Thozhukat Sathyapalan 2 , Khalid Al-Rasadi 3 , Tannaz Jamialahmadi 4, 5, 6 , Amirhossein Sahebkar 4, 7, 8, 9
Affiliation  

Coronary artery diseases (CAD), as a leading cause of mortality around the world, has attracted the researchers’ attention for years to find out its underlying mechanisms and causes. Among the various key players in the pathogenesis of CAD cytokines, microRNAs (miRNAs) are crucial. In this study, besides providing a comprehensive overview of the involvement of cytokines, growth factors, and miRNAs in CAD, the interplay between miRNA with cytokine or growth factors during the development of CAD is discussed.

中文翻译:

MicroRNA在调节冠状动脉疾病中细胞因子和生长因子中的作用:来龙去脉。

冠状动脉疾病(CAD)作为全球主要的死亡原因,多年来一直吸引研究人员的注意力,以找出其潜在的机制和病因。在CAD细胞因子发病机理的各种关键因素中,微小RNA(miRNA)至关重要。在这项研究中,除了提供对细胞因子,生长因子和miRNA在CAD中的参与的全面概述之外,还讨论了miRNA与CAD形成过程中细胞因子或生长因子之间的相互作用。
更新日期:2020-07-25
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