Together with the enhancement of the load-bearing implant process for bone substitution and reproduction, an increasing requirement was observed concerning biodegradable magnesium and its alloys with lighter density and outstanding characteristics. Regardless of the current great potential of Mg utilization currently, the broader use of Mg alloys continues to be constrained by several natural causes, such as low resistance of corrosion, inadequate mechanical integrity during the healing process, and poor antibacterial performance. In this perspective, Mg-based composite encapsulated within graphene family nanomaterials (GFNs) such as graphene (Gr), graphene oxide (GO), graphene nanoplatelets (GNPs), and reduced graphene oxide (rGO) as reinforcement agents present great antibacterial activity, as well as cellular response and depicted numerous benefits for biomedical use. Magnesium matrix nanocomposites reinforced with GFNs possess enhanced mechanical properties and high corrosion resistance (low concentration graphene). It is worth noting that numerous elements including the production technique of the Mg-based composite containing GFNs and the size, distribution, and amounts of GFNs in the Mg-based matrix have a crucial role in their properties and applications. Then, the antibacterial mechanisms of GFN-based composite are briefly described. Subsequently, the antibacterial and strengthening mechanisms of GFN-embedded Mg-based composites are briefly described. This review article is designed to wrap up and explore the most pertinent research performed in the direction of Mg-based composites encapsulated within GFNs. Feasible upcoming investigation directions in the field of GFN-embedded Mg-based composites are discussed in detail.

中文翻译：

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石墨烯家族纳米材料增强镁基生物医学应用基质复合材料：综述

伴随着用于骨骼替代和繁殖的承重植入过程的增强，人们对具有更轻密度和出色特性的可生物降解镁及其合金的需求日益增加。不管当前使用Mg的当前潜力如何，Mg合金的广泛使用仍然受到多种自然原因的限制，例如低的耐腐蚀性，愈合过程中的机械完整性不足以及较差的抗菌性能。从这个角度来看，封装在石墨烯家族纳米材料（GFN）（例如石墨烯（Gr），氧化石墨烯（GO），石墨烯纳米片（GNP）和还原型氧化石墨烯（rGO））中的镁基复合材料具有很大的抗菌活性，以及细胞反应，并描述了生物医学用途的众多好处。GFN增强的镁基纳米复合材料具有增强的机械性能和高耐腐蚀性（低浓度石墨烯）。值得注意的是，包括含GFN的Mg基复合材料的生产技术以及Mg基基质中GFN的尺寸，分布和数量在内的众多元素在其性能和应用中都起着至关重要的作用。然后，简要介绍了基于GFN的复合材料的抗菌机理。随后，简要介绍了GFN嵌入的Mg基复合材料的抗菌和增强机理。这篇综述文章旨在总结和探索在GFN内封装的基于Mg的复合材料方面最相关的研究。