Proliferative disorders of lymphatic origin in animals are mostly congenital or occur within the first few months of life. Involvement of internal organs is extremely infrequent. A seven-year-old entire female mixed-breed dog was presented with apathy and poor appetite. Abdominal ultrasonography revealed a focally enlarged spleen with an anechoic round lesion. Splenectomy was performed and pathological examination demonstrated a sponge-like, compressible tumour composed of endothelium-lined vascular cystic spaces filled with eosinophilic proteinaceous material lacking erythrocytes. Immunohistochemical stains showed that cyst-lining cells were strongly positive for CD31 and factor VIII and focally positive for lymphatic vessel endothelial hyaluronan receptor 1 (LYVE-1). Based on these findings, the lesion was identified as splenic cystic lymphangioma. To the best of our knowledge, this is the first description of solitary lymphangioma of the spleen in animals.

动物淋巴源性增生性疾病大多是先天性的，或在生命的最初几个月内发生。内脏器官很少发生。一只七岁的雌性全犬种表现出冷漠和食欲不振。腹部超声检查显示脾脏有局灶性扩大，伴无回声的圆形病变。进行脾切除术并进行病理检查，发现海绵状可压缩肿瘤由内皮衬里的血管性囊性间隙组成，充满了缺乏红细胞的嗜酸性蛋白物质。免疫组织化学染色显示，囊壁细胞对CD31和VIII因子呈强阳性，对淋巴管内皮透明质酸受体1（LYVE-1）呈局部阳性。根据这些发现，该病灶被鉴定为脾囊性淋巴管瘤。据我们所知，这是对动物脾中孤立性淋巴管瘤的首次描述。