Cyanobacteria blooms and associated cyanotoxins pose significant public health risks during water recreation. Oral ingestion is the only recognized route of toxin exposure in water recreation guidelines. This review examines human skin as a barrier for the prevention of cyanotoxin absorption and investigates the likelihood of negative health effects through dermal exposure. Epidemiological studies of health effects from recreational exposure to algal blooms and toxins are summarized to highlight the importance of better understanding the toxicological effect of dermal exposure. The ability of a specific cyanotoxin to penetrate human skin is inferred by its physiochemical properties according to transdermal drug studies. The review identifies a disparity between the human health effects described in algal bloom exposure case studies and the toxicological skin exposure data. Skin penetration by algal toxins is likely and deserves further investigation.

蓝藻水华和相关的蓝藻毒素在水上娱乐期间构成重大的公共健康风险。饮水是水休闲指南中唯一公认的毒素接触途径。这篇评论审查了人类皮肤作为防止蓝藻毒素吸收的障碍，并研究了通过皮肤暴露对健康产生负面影响的可能性。总结了休闲性接触藻华和毒素对健康的影响的流行病学研究，突显了更好地了解皮肤接触的毒理学作用的重要性。根据透皮药物研究，特定的氰毒素穿透人体皮肤的能力是由其理化特性来推断的。该审查确定了藻华暴露案例研究中描述的人类健康影响与皮肤毒理学数据之间的差异。藻类毒素可能会渗透皮肤，值得进一步研究。