Biodegradable zinc alloy stents offer a prospective solution to mitigate incompatibility between artery and permanent stents. However, biodegradable stents are restricted in clinical therapy mainly because of their insufficient support for opening of stenotic vessel. As an effort to resolve this challenging problem, a novel structure of zinc alloy stent which significantly enhanced scaffold performance is proposed in this paper. Subsequently, the functionality of the new stent on reshaping vessels with 40% of stenosis was investigated in contrast with a common stent via finite element analysis. The simulation results show that radial recoiling ratio and dog-boning ratio of the new stent are decreased by 43.2% and 16.3%, respectively, compared with those of the common stent. A larger and flatter lumen is found in the plaque-vessel system deployed with the new stent. It suggests that the geometry of stent has strong influence on its mechanical performance. With strong scaffold capability and brilliant effect on reshaping stenotic vessel, the biodegradable zinc alloy stent-based novel structure is highly promised to be an alternative choice in interventional surgeries.

中文翻译：

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一种新型可降解锌合金支架结构设计及其对狭窄血管重塑的影响

可生物降解的锌合金支架为减轻动脉支架和永久性支架之间的不相容性提供了一种前瞻性的解决方案。然而，可生物降解支架在临床治疗中受到限制，主要是因为它们对打开狭窄血管的支持不足。为了解决这一具有挑战性的问题，本文提出了一种新型锌合金支架结构，可显着提高支架性能。随后，通过有限元分析与普通支架相比，研究了新支架在重塑具有 40% 狭窄的血管上的功能。仿真结果表明，与普通支架相比，新型支架的径向回缩率和狗骨率分别降低了43.2%和16.3%。在与新支架一起部署的斑块血管系统中发现了更大更平坦的管腔。这表明支架的几何形状对其力学性能有很大的影响。具有强大的支架能力和重塑狭窄血管的显着效果，基于生物可降解锌合金支架的新型结构有望成为介入手术的替代选择。