当前位置: X-MOL 学术J. Bioinform. Comput. Biol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Modeling the impact of point mutations on the stability of proteins
Journal of Bioinformatics and Computational Biology ( IF 0.9 ) Pub Date : 2020-03-30 , DOI: 10.1142/s0219720020500195
K G Kulikov 1 , T V Koshlan 2
Affiliation  

A new method has been introduced which allows us to determine the stability of protein complexes with point changes of amino acid residues that also take into account the three-dimensional structure of the complex. This formulated and proven theorem is aimed at determining the criterion for the stability of protein molecules. The algorithm and software package were developed for analyzing protein interactions, taking into account their three-dimensional structure from the PDB database.

中文翻译:

模拟点突变对蛋白质稳定性的影响

引入了一种新方法,该方法使我们能够确定蛋白质复合物的稳定性,氨基酸残基的点变化也考虑到复合物的三维结构。这个公式化和证明的定理旨在确定蛋白质分子稳定性的标准。该算法和软件包是为分析蛋白质相互作用而开发的,考虑到它们来自 PDB 数据库的三维结构。
更新日期:2020-03-30
down
wechat
bug