In this study, the synthesis of pyrrolo[2,3-c]quinoline as a common skeleton, is described. The process is based on the thermal electrocyclization of 3-phenylpyrrole containing isocyanate as 2-azahexatriene. Using this approach, the total synthesis of three natural marinoquinolines A, B, and E can be successfully achieved.



中文翻译：

---

吡咯并[2,3-C]喹啉生物碱Marinoquinolines的合成

在这项研究中，描述了作为常见骨架的吡咯并[2,3- c ]喹啉的合成。该方法基于含有异氰酸酯作为2-氮杂己三烯的3-苯基吡咯的热电环化。使用这种方法，可以成功地完成三种天然马林喹啉A，B和E的全合成。