Zika virus (ZIKV) is a newly emergent relative of the Flaviviridae family and linked to dengue (DENV) and Chikungunya (CHIVKV). ZIKV is one of the rising pathogens promptly surpassing geographical borders. ZIKV infection was characterized by mild disease with fever, headache, rash, arthralgia and conjunctivitis, with exceptional reports of an association with Guillain–Barre syndrome (GBS) and microcephaly. However, since the end of 2015, an increase in the number of GBS associated cases and an astonishing number of microcephaly in fetus and new-borns in Brazil have been related to ZIKV infection, raising serious worldwide public health concerns. ZIKV is transmitted by the bite of infected female mosquitoes of Aedes species. Clarifying such worrisome relationships is, thus, a current unavoidable goal. Here, we extensively described the current understanding of the effects of ZIKV on heath, clinical manifestation, diagnosis and treatment options based on modern, alternative and complementary medicines regarding the disease.

中文翻译：

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寨卡病毒爆发，流行病学，传播和感染动态的评论

寨卡病毒（ZIKV）是黄病毒科的一个新近出现的亲戚，与登革热（DENV）和基孔肯雅热（CHIVKV）相关。ZIKV是迅速超越地理边界的新兴病原体之一。ZIKV感染的特征是轻度疾病，包括发烧，头痛，皮疹，关节痛和结膜炎，并有异常报道涉及格林-巴利综合征（GBS）和小头畸形。然而，自2015年底以来，与GBS相关的病例数量增加，巴西胎儿和新生儿的小头畸形数量也与ZIKV感染有关，这引起了全球范围内严重的公共卫生问题。ZIKV是通过被伊蚊物种的雌性蚊子叮咬传播的。因此，弄清这种令人担忧的关系是当前不可避免的目标。这里，