In the years of personalized (or precision) medicine the ‘omics’ methodologies in biomedical sciences—genomics, transcriptomics, proteomics and metabolomics—are helping researchers to detect quantifiable biological characteristics, or biomarkers, that will best define the human physiology and pathologies. Proteomics use high throughput and high efficiency approaches with the support of bioinformatic tools in order to identify and quantify the total protein content of cells, tissues or biological fluids. Saliva receives a lot of attention as a rich biological specimen that offers a number of practical and physiological advantages over blood and other biological fluids in monitoring human health. The aim of this review is to present the latest advances in saliva proteomics for biomedicine.

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唾液蛋白质组学在生物医学中的更新

在个性化（或精密）医学的年代，生物医学科学中的“组学”方法论（基因组学，转录组学，蛋白质组学和代谢组学）正在帮助研究人员检测可最佳定义人类生理学和病理学的可量化生物学特征或生物标志物。蛋白质组学在生物信息学工具的支持下使用高通量和高效方法来鉴定和定量细胞，组织或生物体液的总蛋白质含量。唾液作为一种丰富的生物标本受到了广泛的关注，它在监测人体健康方面比血液和其他生物液体具有许多实用和生理优势。这篇综述的目的是介绍生物医学唾液蛋白质组学的最新进展。