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Insights into the draft genome sequence of bioactives-producing Bacillus thuringiensis DNG9 isolated from Algerian soil-oil slough
Environmental Microbiome ( IF 6.2 ) Pub Date : 2018-10-11 , DOI: 10.1186/s40793-018-0331-1
Mohamed Seghir Daas , Albert Remus R. Rosana , Jeella Z. Acedo , Malika Douzane , Farida Nateche , Salima Kebbouche-Gana , John C. Vederas

Bacillus thuringiensis is widely used as a bioinsecticide due to its ability to form parasporal crystals containing proteinaceous toxins. It is a member of the Bacillus cereus sensu lato, a group with low genetic diversity but produces several promising antimicrobial compounds. B. thuringiensis DNG9, isolated from an oil-contaminated slough in Algeria, has strong antibacterial, antifungal and biosurfactant properties. Here, we report the 6.06 Mbp draft genome sequence of B. thuringiensis DNG9. The genome encodes several gene inventories for the biosynthesis of bioactive compounds such as zwittermycin A, petrobactin, insecticidal toxins, polyhydroxyalkanoates and multiple bacteriocins. We expect the genome information of strain DNG9 will provide another model system to study pathogenicity against insect pests, plant diseases, and antimicrobial compound mining and comparative phylogenesis among the Bacillus cereus sensu lato group.

中文翻译:

从阿尔及利亚土壤-油泥中分离出生物活性的苏云金芽孢杆菌DNG9基因组序列草案的见解

苏云金芽孢杆菌由于能够形成含有蛋白质毒素的孢子旁晶体而被广泛用作生物杀虫剂。它是蜡样芽孢杆菌的成员,该物种遗传多样性低,但会产生几种很有希望的抗菌化合物。苏云金芽孢杆菌DNG9分离自阿尔及利亚的一个被油污染的泥沼,具有很强的抗菌,抗真菌和生物表面活性剂性能。在这里,我们报告了苏云金芽孢杆菌DNG9的6.06 Mbp草案基因组序列。该基因组编码了几种生物活性化合物(如两性霉素A,石蜡菌素,杀虫毒素,多羟基链烷酸酯和多种细菌素)的生物合成基因清单。我们希望DNG9菌株的基因组信息将提供另一个模型系统,以研究对害虫,植物病害,
更新日期:2018-10-11
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