Abstract

Digoxin separation from pharmaceuticals wastes, is small piece of the larger puzzle in holistic risk assessment. In this study, a novel magnetic nano composite (graphene oxide/Fe₃O₄/SO₃H) was synthesized and used as an absorbent for the removal of digoxin from aqueous solution. We utilized UV-Vis spectrophotometry (UV/Vis) for detection and efficient removal of digoxin by magnetic graphene oxide (MGO) in different concentrations. Magnetic absorbent was characterized by thermal gravimetric analysis (TGA), Fourier-transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD). The optimized concentration of absorbent and digoxin were 500 and 1 ppm respectively, in which the optimize reaction time was lasting 10 min. Finally, under optimized condition, MGO was used for the efficient separation of digoxin from aqueous solution.

摘要

地高辛与制药废料的分离只是整体风险评估中一个比较大的难题。在这项研究中，一种新型的磁性纳米复合材料（氧化石墨烯/ Fe ₃ O ₄ / SO ₃H）被合成并用作吸收剂以从水溶液中去除地高辛。我们利用紫外可见分光光度法（UV / Vis）通过不同浓度的磁性氧化石墨烯（MGO）检测和有效去除地高辛。通过热重分析（TGA），傅立叶变换红外光谱（FTIR）和X射线衍射（XRD）对磁性吸收剂进行了表征。吸收剂和地高辛的最适浓度分别为500和1 ppm，其中最适反应时间持续10分钟。最后，在优化条件下，MGO用于从水溶液中有效分离地高辛。