Abstract

Nanomaterials comprise extraordinary physicochemical and biological properties for therapeutic applications including three-dimensional porous structures as scaffolds for tissue engineering and as controlled release drug/gen delivery vehicles due to their small size, large surface area, and ability to interact with cells/tissues. Carbon-based nanostructures such as graphene, carbon nanotube, and nanodiamond have attracted both academic and industrial interest because they improve the chemical, mechanical, and biological properties to cellular adhesion tendency of different natural and synthetic polymers in bioapplication. This review covers the fabrication technique of carbon nanostructures and the development of carbon-based nanostructured polymer composites for application in drug/gen delivery and tissue engineering.

摘要

纳米材料具有用于治疗应用的非凡物理化学和生物学特性，包括作为组织工程支架和控释药物/基因传递载体的三维多孔结构，因为它们具有小尺寸、大表面积和与细胞/组织相互作用的能力。石墨烯、碳纳米管和纳米金刚石等碳基纳米结构在生物应用中改善了不同天然和合成聚合物对细胞粘附趋势的化学、机械和生物特性，因此引起了学术界和工业界的兴趣。本综述涵盖了碳纳米结构的制造技术以及用于药物/基因传递和组织工程的碳基纳米结构聚合物复合材料的开发。