Abstract The linearized evaporative light scattering detector (ELSD) allows the evaluation of molecular weight distributions (MWD) of a range of polymers using conventional gel permeation chromatography (GPC), and is a suitable replacement for the differential refractive index (DRI) detector in applications which will benefit from fast equilibration, solvent gradients or when working with low polymer concentrations. Further, when DRI is coupled with a viscometer, the Universal Calibration GPC method also allows the evaluation of Mark–Houwink–Sakurada parameters K and alpha, which provides valuable information on the chemical structure of polymer chains. Therefore, for a wider acceptance of ELSD in GPC, we investigated the possibility of coupling the ELSD with the viscometer. Recommendations are provided for successfully coupling the ELSD and viscometer, as well as on software adjustments to calculate K and alpha parameters. For linear polyethylene, a good correlation was found between the measured and the expected K and alpha values.

中文翻译：

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使用蒸发光散射检测器和粘度计对凝胶渗透色谱进行通用校准

摘要 线性化蒸发光散射检测器 (ELSD) 允许使用常规凝胶渗透色谱 (GPC) 评估一系列聚合物的分子量分布 (MWD)，并且在应用中是差示折光 (DRI) 检测器的合适替代品这将受益于快速平衡、溶剂梯度或使用低聚合物浓度时。此外，当 DRI 与粘度计结合使用时，通用校准 GPC 方法还可以评估 Mark-Houwink-Sakurada 参数 K 和 alpha，这提供了有关聚合物链化学结构的宝贵信息。因此，为了在 GPC 中更广泛地接受 ELSD，我们研究了将 ELSD 与粘度计耦合的可能性。提供了成功连接 ELSD 和粘度计的建议，以及用于计算 K 和 alpha 参数的软件调整。对于线性聚乙烯，在测量值和预期 K 值和 alpha 值之间发现了良好的相关性。