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Mechanical behavior of hydroxyapatite-poly(lactic acid) hybrid porous scaffold
Advanced Composite Materials ( IF 1.8 ) Pub Date : 2020-06-01 , DOI: 10.1080/09243046.2020.1759183
Yu Zusho 1 , Satoshi Kobayashi 1 , Toshiko Osada 1
Affiliation  

Although autologous bone is currently used for repairing bone defects, this method is highly invasive and poses a heavy burden on patients. Thus, the use of artificial bones has been expected. Among the artificial bone materials, bioactive hydroxyapatite (HA) has been attracting much attention. In this research, in order to overcome the problem such as low initial strength of artificial bone after implantation, poly(lactic acid) (PLA) was coated on HA unidirectional porous body prepared by freeze-casting method. In order to investigate the PLA coating method that most effectively improves the mechanical properties, the coating state of PLA was observed and the compression test was performed. As a result of the compression test of the HA-PLA composite porous body, Young’s modulus and compressive strength were improved by 79% and 184% respectively at maximum. Furthermore, acoustic emission (AE) measurement was conducted to investigate the fracture behavior during the compression test, classifying the main fracture of HA and HA-PLA porous body as shear fracture.

中文翻译:

羟基磷灰石-聚乳酸杂化多孔支架的力学行为

虽然目前使用自体骨修复骨缺损,但这种方法具有高侵入性,给患者带来了沉重的负担。因此,期待使用人造骨。在人造骨材料中,生物活性羟基磷灰石(HA)备受关注。本研究为克服人工骨植入后初始强度低等问题,将聚乳酸(PLA)包覆在冷冻浇注法制备的HA单向多孔体上。为了研究最有效提高机械性能的 PLA 涂层方法,观察了 PLA 的涂层状态并进行了压缩试验。作为 HA-PLA 复合多孔体的压缩试验结果,杨氏模量和抗压强度最大分别提高了 79% 和 184%。此外,进行声发射 (AE) 测量以研究压缩试验期间的断裂行为,将 HA 和 HA-PLA 多孔体的主要断裂归类为剪切断裂。
更新日期:2020-06-01
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