Chronic asthma is a heterogeneous disease, and increased eosinophils have been shown to predict increased asthma exacerbations, especially in adults. Recent recommendations suggest the need for supplemental PPV‐23 vaccination in older children with chronic asthma.

中文翻译：

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肺炎球菌疫苗反应对幼儿哮喘发作频率的影响。

慢性哮喘是一种异质性疾病，嗜酸性粒细胞增多已被证明可预测哮喘加重的增加，尤其是在成人中。最近的建议表明需要对患有慢性哮喘的年龄较大的儿童进行补充 PPV-23 疫苗接种。