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Future antiviral surfaces: Lessons from COVID-19 pandemic
Sustainable Materials and Technologies ( IF 8.6 ) Pub Date : 2020-09-01 , DOI: 10.1016/j.susmat.2020.e00203
Ziqi Sun , Kostya (Ken) Ostrikov

Abstract It is an urgent priority for advanced materials researchers to help find solutions to eliminate the COVID-19 pandemic. The transmission of the SARS-CoV-2 coronavirus is majorly through touching the contaminated surfaces and then the vulnerable mouth and eyes besides the direct contact with the infected person. This lesson inspired us to propose a strategy from the view of materials scientists on designing effective antiviral surfaces to prevent the transmission of infectious coronaviruses by disrupting their survival on various surfaces. In this review, based on current progress in antiviral and antibacterial coatings, we put forward some general principles for designing effective antiviral surfaces by applying natural viral inhibitors, physical/chemical modifications, and bioinspired patterns, with the mechanisms of direct disinfection, indirect disinfection, and receptor inactivation. This work maps possible solutions to inactivate the receptors of the coronavirus spikes and resist the transmission of the COVID-19 and other infectious diseases, and contribute to the prevention of future outbreaks and control of epidemics.

中文翻译:

未来的抗病毒表面:来自 COVID-19 大流行的教训

摘要 帮助寻找消除 COVID-19 大流行的解决方案是先进材料研究人员的当务之急。SARS-CoV-2冠状病毒的传播主要是通过接触受污染的表面,然后是接触易受感染的嘴巴和眼睛,除了与感染者直接接触。这一课启发我们从材料科学家的角度提出了一种策略,即设计有效的抗病毒表面,通过破坏冠状病毒在各种表面上的存活来防止其传播。在这篇综述中,基于当前抗病毒和抗菌涂层的进展,我们提出了一些通过应用天然病毒抑制剂、物理/化学修饰和仿生模式设计有效抗病毒表面的一般原则,以及直接消毒的机制,间接消毒和受体灭活。这项工作绘制了可能的解决方案,以灭活冠状病毒尖峰的受体并抵抗 COVID-19 和其他传染病的传播,并有助于预防未来的爆发和流行病的控制。
更新日期:2020-09-01
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