Metastasis and metabolism reprogramming are two major hallmarks of cancer. In the initiation and progression of cancer, tumor cells are known to undergo fundamental metabolic changes to sustain their development and progression. In recent years, much more attentions have been drawn to their important roles in facilitating cancer metastasis through regulating the biological properties. In this review, we summarized the recent progresses in the studies of metabolism reprogramming of cancer metastasis, particularly of primary liver cancer, and highlight their potential applications.

中文翻译：

---

燃料和引擎：重新编程的代谢在原发性肝癌转移中的作用。

转移和代谢重编程是癌症的两个主要标志。在癌症的发生和发展中，已知肿瘤细胞经历基本的代谢变化以维持其发展和进展。近年来，人们越来越关注它们在通过调节生物学特性而促进癌症转移中的重要作用。在这篇综述中，我们总结了癌症转移特别是原发性肝癌的新陈代谢的代谢重编程研究的最新进展，并强调了它们的潜在应用。