An appropriate connection of the cells in the ovary follicles is vital for a healthy ovule maturation and fertilization, and also for endometrium preparation for implantation that can cause endometriosis. Cellular communication within the follicle and endometrial epithelium involve many signaling molecules. Recent studies indicate that cellular communication can be enclosed by secretion and absorption of small membrane carriers which are named extracellular vesicles including exosomes and microvesicles. Understanding and defining these EVs (Extracellular vesicles) population are important for future studies and clinical translation. Here, we describe the various important cargos which are carried by exosomes during folliculogenesis and endometriosis. Additionally, the current knowledge of exosomes and their cargo within the FF (Follicular fluid) during the folliculogenesis and also in the intrauterine cavity which are involved in endometriosis lesions have also been summarized. Considering the potential importance of this form of the cell to cell communication in the reproductive system, the vital issues under discussion lead to a new insight in this rapidly expanding field and it may be an interesting approach for diagnostic, prognostic and especially therapeutic strategies in the field of infertility and assisted reproductive technology (ART).

卵巢卵泡中细胞的适当连接对于健康的胚珠成熟和受精以及可能导致子宫内膜异位症的子宫内膜植入准备至关重要。卵泡和子宫内膜上皮内的细胞通讯涉及许多信号分子。最近的研究表明，细胞通讯可以通过被称为细胞外囊泡（包括外泌体和微囊泡）的小膜载体的分泌和吸收来封闭。了解和定义这些 EV（细胞外囊泡）群体对于未来的研究和临床转化很重要。在这里，我们描述了在卵泡发生和子宫内膜异位症期间外泌体携带的各种重要货物。此外，还总结了在卵泡发生期间外泌体及其在 FF（卵泡液）内以及宫腔内与子宫内膜异位症病变有关的外泌体及其货物的知识。考虑到这种形式的细胞间通讯在生殖系统中的潜在重要性，正在讨论的重要问题为这个快速扩展的领域带来了新的见解，它可能是一种有趣的方法，用于诊断、预后，尤其是在生殖系统中的治疗策略。不孕不育和辅助生殖技术（ART）领域。