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Arbutin Content in the Far-Eastern Species Serratula komarovii Iljin
Pharmaceutical Chemistry Journal ( IF 0.8 ) Pub Date : 2020-07-01 , DOI: 10.1007/s11094-020-02207-w
A. V. Myagchilov , S. A. Mineev , L. I. Sokolova , E. D. Gerdasova , P. G. Gorovoi

The biologically active compound arbutin (hydroquinone β-D-glucopyranoside) was isolated for the first time from leaves of Serratula komarovii Iljin growing in Primorsky Krai by solvent extraction (EtOH, 70%) and preparative column chromatography using silica gel (L 230 – 400 mesh) and gradient elution by mixtures of solvents (CCl4 and EtOH). The isolated compound was identified by NMR and IR spectroscopy. The arbutin contents in aerial organs (leaves, stems) of S. komarovii were determined by reversed-phase high-performance liquid chromatography (RP HPLC). The mass fraction of arbutin in leaves was 3.31 ± 0.30%; in stems, 0.49 ± 0.09%. This compound was not detected in aerial organs (leaves, stems) of S. manshurica Kitag.

中文翻译:

远东物种 Serratula komarovii Iljin 中的熊果苷含量

生物活性化合物熊果苷(氢醌β-D-吡喃葡萄糖苷)首次通过溶剂萃取(乙醇,70%)和硅胶制备柱色谱法(L 230 – 400网格)和溶剂(CCl4 和 EtOH)混合物的梯度洗脱。分离的化合物通过NMR和IR光谱鉴定。用反相高效液相色谱法(RP HPLC) 测定了科马罗威松气生器官(叶、茎) 中熊果苷的含量。叶片中熊果苷的质量分数为3.31±0.30%;在茎中,0.49 ± 0.09%。在 S. manshurica Kitag 的气生器官(叶、茎)中未检测到该化合物。
更新日期:2020-07-01
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