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Antimycotic Activity of Naftifine Hydrochloride Solution in Combination with Poly(Ethylene Glycols)
Pharmaceutical Chemistry Journal ( IF 0.8 ) Pub Date : 2020-06-01 , DOI: 10.1007/s11094-020-02196-w
S. I. Kosenkova , I. I. Krasnyuk , I. I. Krasnyuk Jr , A. V. Belyatskaya , O. I. Stepanova , T. Li , T. V. Fateeva , E. V. Mazyarkin , V. V. Novikov , T. V. Korochkina

The microbiological activity of naftifine hydrochloride solution in combination with poly(ethylene glycols) (PEG-400 and PEG-1000) was determined and compared with that of the existing foreign drug Exoderil ® . The results showed that the fungistatic activity (minimum inhibitory concentration) of the proposed solution was about double that of Exoderil solution for Candida albicans ATCC 10231.

中文翻译:

盐酸萘替芬溶液与聚(乙二醇)组合的抗真菌活性

测定了盐酸萘替芬溶液与聚乙二醇(PEG-400 和 PEG-1000)组合的微生物活性,并与现有的国外药物 Exoderil ® 的微生物活性进行了比较。结果表明,对于白色念珠菌 ATCC 10231,所提出的溶液的抑真菌活性(最小抑制浓度)大约是 Exoderil 溶液的两倍。
更新日期:2020-06-01
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